The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis

Synovitis, a common clinical symptom for osteoarthritis (OA) patients, is highly related to OA pathological progression and pain manifestation. The activated synovial macrophages have been demonstrated to play an important role in synovitis, but the mechanisms about macrophage activation are still n...

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Detalles Bibliográficos
Autores principales: Ni, Zhenhong, Kuang, Liang, Chen, Hangang, Xie, Yangli, Zhang, Bin, Ouyang, Junjie, Wu, Jiangyi, Zhou, Siru, Chen, Liang, Su, Nan, Tan, QiaoYan, Luo, Xiaoqing, Chen, Bo, Chen, Shuai, Yin, Liangjun, Huang, Haiyang, Du, Xiaolan, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614358/
https://www.ncbi.nlm.nih.gov/pubmed/31285423
http://dx.doi.org/10.1038/s41419-019-1739-2

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