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EZH2, JMJD3, and UTX epigenetically regulate hepatic plasticity inducing retro-differentiation and proliferation of liver cells

Modification of histones by lysine methylation plays a role in many biological processes, and it is dynamically regulated by several histone methyltransferases and demethylases. The polycomb repressive complex contains the H3K27 methyltransferase EZH2 and controls dimethylation and trimethylation of...

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Detalles Bibliográficos
Autores principales: Pediconi, Natalia, Salerno, Debora, Lupacchini, Leonardo, Angrisani, Annapaola, Peruzzi, Giovanna, De Smaele, Enrico, Levrero, Massimo, Belloni, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614397/
https://www.ncbi.nlm.nih.gov/pubmed/31285428
http://dx.doi.org/10.1038/s41419-019-1755-2