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EZH2, JMJD3, and UTX epigenetically regulate hepatic plasticity inducing retro-differentiation and proliferation of liver cells
Modification of histones by lysine methylation plays a role in many biological processes, and it is dynamically regulated by several histone methyltransferases and demethylases. The polycomb repressive complex contains the H3K27 methyltransferase EZH2 and controls dimethylation and trimethylation of...
Autores principales: | Pediconi, Natalia, Salerno, Debora, Lupacchini, Leonardo, Angrisani, Annapaola, Peruzzi, Giovanna, De Smaele, Enrico, Levrero, Massimo, Belloni, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614397/ https://www.ncbi.nlm.nih.gov/pubmed/31285428 http://dx.doi.org/10.1038/s41419-019-1755-2 |
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