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Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
Human iPSC-derived engineered heart tissue (hEHT) has been used to remuscularize injured hearts in a guinea pig infarction model. While beneficial effects on cardiac remodeling have been demonstrated, the arrhythmogenic potential of hEHTs is a major concern. We investigated whether hiPSC-derived hEH...
Autores principales: | Pecha, Simon, Yorgan, Kaja, Röhl, Matti, Geertz, Birgit, Hansen, Arne, Weinberger, Florian, Sehner, Susanne, Ehmke, Heimo, Reichenspurner, Hermann, Eschenhagen, Thomas, Schwoerer, Alexander Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614415/ https://www.ncbi.nlm.nih.gov/pubmed/31285568 http://dx.doi.org/10.1038/s41598-019-46409-z |
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