Cargando…

A Combined Transcriptomic and Genomic Analysis Identifies a Gene Signature Associated With the Response to Anti-TNF Therapy in Rheumatoid Arthritis

Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients do not show a significant clinical response. The objective of this study was to identify...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aterido, Adrià, Cañete, Juan D., Tornero, Jesús, Blanco, Francisco, Fernández-Gutierrez, Benjamín, Pérez, Carolina, Alperi-López, Mercedes, Olivè, Alex, Corominas, Héctor, Martínez-Taboada, Víctor, González, Isidoro, Fernández-Nebro, Antonio, Erra, Alba, López-Lasanta, María, López Corbeto, Mireia, Palau, Núria, Marsal, Sara, Julià, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614444/ https://www.ncbi.nlm.nih.gov/pubmed/31312201 http://dx.doi.org/10.3389/fimmu.2019.01459

Ejemplares similares

Variation at FCGR2A and Functionally Related Genes Is Associated with the Response to Anti-TNF Therapy in Rheumatoid Arthritis
por: Avila-Pedretti, Gabriela, et al.
Publicado: (2015)

Variation at interleukin-6 receptor gene is associated to joint damage in rheumatoid arthritis
por: Lopez-Lasanta, Maria, et al.
Publicado: (2015)

Genetic variation associated with cardiovascular risk in autoimmune diseases
por: Perrotti, Pedro P., et al.
Publicado: (2017)

Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy
por: Julià, Antonio, et al.
Publicado: (2021)

Genome-wide pathway analysis identifies VEGF pathway association with oral ulceration in systemic lupus erythematosus
por: Aterido, Adrià, et al.
Publicado: (2017)

Longitudinal analysis of blood DNA methylation identifies mechanisms of response to tumor necrosis factor inhibitor therapy in rheumatoid arthritis
por: Julià, Antonio, et al.
Publicado: (2022)

Genome-wide transcriptional analysis of T cell activation reveals differential gene expression associated with psoriasis
por: Palau, Nuria, et al.
Publicado: (2013)

Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus
por: Julià, Antonio, et al.
Publicado: (2018)

Targeting of the CD80/86 proinflammatory axis as a therapeutic strategy to prevent severe COVID-19
por: Julià, Antonio, et al.
Publicado: (2021)

Novel Insights into the Regulatory Architecture of CD4+ T Cells in Rheumatoid Arthritis
por: Aterido, Adrià, et al.
Publicado: (2014)

Incidence of COVID-19 in a cohort of adult and paediatric patients with rheumatic diseases treated with targeted biologic and synthetic disease-modifying anti-rheumatic drugs
por: Michelena, Xabier, et al.
Publicado: (2020)

IMID-Biobank: Biobank of immune-mediated inflammatory diseases (IMIDs)
por: Marsal, S, et al.
Publicado: (2010)

A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis
por: Torices, Silvia, et al.
Publicado: (2016)

Systemic Lupus Erythematosus: Genomics, Mechanisms, and Therapies
por: Fernández-Nebro, Antonio, et al.
Publicado: (2012)

Urine metabolome profiling of immune-mediated inflammatory diseases
por: Alonso, Arnald, et al.
Publicado: (2016)

Rituximab reduces the hospitalization in patients with systemic lupus erythematosus
por: Martínez-Pérez, R, et al.
Publicado: (2010)

Cardiovascular disease in immune-mediated inflammatory diseases: A cross-sectional analysis of 6 cohorts
por: Fernández-Gutiérrez, Benjamín, et al.
Publicado: (2017)

Lower peripheral helper T cell levels in the synovium are associated with a better response to anti-TNF therapy in rheumatoid arthritis
por: Julià, Antonio, et al.
Publicado: (2020)

An Eight-Gene Blood Expression Profile Predicts the Response to Infliximab in Rheumatoid Arthritis
por: Julià, Antonio, et al.
Publicado: (2009)

Situación epidemiológica de las infecciones de transmisión sexual pospandemia en Cataluña, España
por: López Corbeto, Evelin, et al.
Publicado: (2023)

Efectos a corto plazo de un brote inicial de COVID-19 en la atención del cáncer de mama
por: Barco Nebreda, Israel, et al.
Publicado: (2023)

Short term effects of an initial COVID-19 outbreak on breast cancer care. A brief report
por: Barco Nebreda, Israel, et al.
Publicado: (2023)

CNstream: A method for the identification and genotyping of copy number polymorphisms using Illumina microarrays
por: Alonso, Arnald, et al.
Publicado: (2010)

Non-Esterified Fatty Acids Profiling in Rheumatoid Arthritis: Associations with Clinical Features and Th1 Response
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2016)

Heterogeneity of the Type I Interferon Signature in Rheumatoid Arthritis: A Potential Limitation for Its Use As a Clinical Biomarker
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2018)

Profiling of B-Cell Factors and Their Decoy Receptors in Rheumatoid Arthritis: Association With Clinical Features and Treatment Outcomes
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2018)

Primary respiratory disease in patients with systemic lupus erythematosus: data from the Spanish rheumatology society lupus registry (RELESSER) cohort
por: Narváez, Javier, et al.
Publicado: (2018)

A young girl with severe polyarteritis nodosa successfully treated with tocilizumab: a case report
por: Boistault, Margaux, et al.
Publicado: (2021)

Do NSAIDs Take Us Away From Treatment Goals in Axial Spondyloarthritis: A Story About Dysbiosis or Just a Matter of Bias?
por: Queiro-Silva, Rubén, et al.
Publicado: (2021)

IRF4 and IRGs Delineate Clinically Relevant Gene Expression Signatures in Systemic Lupus Erythematosus and Rheumatoid Arthritis
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2019)

Thriving beneath olive trees: The influence of organic farming on microbial communities
por: Wentzien, Nuria M., et al.
Publicado: (2023)

Synovial fibroblast hyperplasia correlates with rheumatoid arthritis duration and activity and is partially reversed by anti-TNF therapy
por: Izquierdo, E, et al.
Publicado: (2010)

Functional rare variants influence the clinical response to anti-TNF therapy in Crohn’s disease
por: Chaparro, María, et al.
Publicado: (2019)

GlycA Levels during the Earliest Stages of Rheumatoid Arthritis: Potential Use as a Biomarker of Subclinical Cardiovascular Disease
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2020)

Prevalence and predictive factors of Chlamydia trachomatis genital infection in inmates 25 to 65 years old in four Catalan prisons
por: Carnicer-Pont, D, et al.
Publicado: (2019)

IFNα Serum Levels Are Associated with Endothelial Progenitor Cells Imbalance and Disease Features in Rheumatoid Arthritis Patients
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2014)

The impact of the COVID-19 pandemic on Sexually Transmitted Infections surveillance data: incidence drop or artefact?
por: Sentís, Alexis, et al.
Publicado: (2021)

Selected reaction monitoring assays in mesenchymal stem cells from osteoarthritis patients
por: Camafeita, Emilio, et al.
Publicado: (2014)

Integrative Clinical, Molecular, and Computational Analysis Identify Novel Biomarkers and Differential Profiles of Anti-TNF Response in Rheumatoid Arthritis
por: Luque-Tévar, Maria, et al.
Publicado: (2021)

Infección pulmonar por Actinomyces diagnosticada mediante ecobroncoscopia lineal. Correlación con los hallazgos histopatológicos
por: Barreiro López, Bienvenido, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_37shqjru59r2dm12mrc423l31t