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A Plant-Produced in vivo deglycosylated full-length Pfs48/45 as a Transmission-Blocking Vaccine Candidate against malaria

Pfs48/45 is a leading antigen candidate for a transmission blocking (TB) vaccine. However, efforts to produce affordable, safe and correctly folded full-length Pfs48/45 using different protein expression systems have not produced an antigen with satisfactory TB activity. Pfs48/45 has 16 cysteines in...

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Detalles Bibliográficos
Autores principales:	Mamedov, Tarlan, Cicek, Kader, Miura, Kazutoyo, Gulec, Burcu, Akinci, Ersin, Mammadova, Gunay, Hasanova, Gulnara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614448/ https://www.ncbi.nlm.nih.gov/pubmed/31285498 http://dx.doi.org/10.1038/s41598-019-46375-6

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