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AgBR1 antibodies delay lethal Aedes aegypti-borne West Nile virus infection in mice

West Nile virus (WNV) is transmitted by mosquitoes and can cause severe disease, including meningoencephalitis. AgBR1 is a mosquito salivary protein that enhances Aedes aegypti mosquito-borne Zika virus pathogenesis in mice. Here, we show that AgBR1 antibodies reduce the initial West Nile viral load...

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Detalles Bibliográficos
Autores principales: Uraki, Ryuta, Hastings, Andrew K., Brackney, Doug E., Armstrong, Philip M., Fikrig, Erol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614468/
https://www.ncbi.nlm.nih.gov/pubmed/31312526
http://dx.doi.org/10.1038/s41541-019-0120-x