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Feasability of Introducing a Thioether Ring in Vasopressin by nisBTC Co-expression in Lactococcus lactis

Introducing one or more intramolecular thioether bridges in a peptide provides a promising approach to create more stable molecules with improved pharmacodynamic properties and especially to protect peptides against proteolytic degradation. Lanthipeptides are compounds that naturally possess thioeth...

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Detalles Bibliográficos
Autores principales: Li, Qian, Montalban-Lopez, Manuel, Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614560/
https://www.ncbi.nlm.nih.gov/pubmed/31333616
http://dx.doi.org/10.3389/fmicb.2019.01508