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Feasability of Introducing a Thioether Ring in Vasopressin by nisBTC Co-expression in Lactococcus lactis
Introducing one or more intramolecular thioether bridges in a peptide provides a promising approach to create more stable molecules with improved pharmacodynamic properties and especially to protect peptides against proteolytic degradation. Lanthipeptides are compounds that naturally possess thioeth...
Autores principales: | Li, Qian, Montalban-Lopez, Manuel, Kuipers, Oscar P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614560/ https://www.ncbi.nlm.nih.gov/pubmed/31333616 http://dx.doi.org/10.3389/fmicb.2019.01508 |
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