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High glucose promotes annulus fibrosus cell apoptosis through activating the JNK and p38 MAPK pathways
Diabetes mellitus (DM) is an important risk factor of intervertebral disc degeneration. A high glucose niche-mediated disc cell apoptosis is an implicate causative factor for the spine degenerative diseases related with DM. However, the effects of a high glucose niche on disc annulus fibrosus (AF) c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614572/ https://www.ncbi.nlm.nih.gov/pubmed/31221817 http://dx.doi.org/10.1042/BSR20190853 |