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High glucose promotes annulus fibrosus cell apoptosis through activating the JNK and p38 MAPK pathways

Diabetes mellitus (DM) is an important risk factor of intervertebral disc degeneration. A high glucose niche-mediated disc cell apoptosis is an implicate causative factor for the spine degenerative diseases related with DM. However, the effects of a high glucose niche on disc annulus fibrosus (AF) c...

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Detalles Bibliográficos
Autores principales: Shan, Lizhen, Yang, Di, Zhu, Danjie, Feng, Fabo, Li, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614572/
https://www.ncbi.nlm.nih.gov/pubmed/31221817
http://dx.doi.org/10.1042/BSR20190853

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