Necrotic leg ulcers secondary to hydrophilic polymer gel emboli

A 63-year-old man presented with left lower extremity ischemia and pain. Left lower extremity angiography revealed calcification throughout the superficial femoral artery, prompting atherectomy and angioplasty with a drug-coated balloon. About 1 week after the procedure, he developed angulated ulcers with central eschar on the left lower extremity and was referred to the dermatology clinic. A biopsy showed cutaneous intravascular foreign material consistent with hydrophilic polymer gel. In patients who develop retiform purpura and ulcerations after endovascular procedures, the diagnosis of hydrophilic polymer embolus should be considered. Treatment consists of supportive care, making early identification vital to avoid unnecessary amputation.