MORC3 Forms Nuclear Condensates through Phase Separation

Phase separation can produce local structures with specific functionality in the cell, and in the nucleus, this can lead to chromatin reorganization. Microrchidia 3 (MORC3) is a human ATPase that has been implicated in autoimmune disorders and cancer. Here, we show that MORC3 forms phase-separated c...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Bertulat, Bianca, Tencer, Adam H., Ren, Xiaojun, Wright, Gregory M., Black, Joshua, Cardoso, M. Cristina, Kutateladze, Tatiana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614601/
https://www.ncbi.nlm.nih.gov/pubmed/31284181
http://dx.doi.org/10.1016/j.isci.2019.06.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614601/
https://www.ncbi.nlm.nih.gov/pubmed/31284181
http://dx.doi.org/10.1016/j.isci.2019.06.030

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