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MORC3 Forms Nuclear Condensates through Phase Separation
Phase separation can produce local structures with specific functionality in the cell, and in the nucleus, this can lead to chromatin reorganization. Microrchidia 3 (MORC3) is a human ATPase that has been implicated in autoimmune disorders and cancer. Here, we show that MORC3 forms phase-separated c...
Autores principales: | Zhang, Yi, Bertulat, Bianca, Tencer, Adam H., Ren, Xiaojun, Wright, Gregory M., Black, Joshua, Cardoso, M. Cristina, Kutateladze, Tatiana G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614601/ https://www.ncbi.nlm.nih.gov/pubmed/31284181 http://dx.doi.org/10.1016/j.isci.2019.06.030 |
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