Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells

Defects in mitotic spindle orientation (MSO) disrupt the organization of stem cell niches impacting tissue morphogenesis and homeostasis. Mutations in centrosome genes reduce MSO fidelity, leading to tissue dysplasia and causing several diseases such as microcephaly, dwarfism, and cancer. Whether th...

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Detalles Bibliográficos
Autores principales: Gambarotto, Davide, Pennetier, Carole, Ryniawec, John M., Buster, Daniel W., Gogendeau, Delphine, Goupil, Alix, Nano, Maddalena, Simon, Anthony, Blanc, Damien, Racine, Victor, Kimata, Yuu, Rogers, Gregory C., Basto, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614718/
https://www.ncbi.nlm.nih.gov/pubmed/31130353
http://dx.doi.org/10.1016/j.devcel.2019.04.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614718/
https://www.ncbi.nlm.nih.gov/pubmed/31130353
http://dx.doi.org/10.1016/j.devcel.2019.04.036

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