Cargando…

Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells

Defects in mitotic spindle orientation (MSO) disrupt the organization of stem cell niches impacting tissue morphogenesis and homeostasis. Mutations in centrosome genes reduce MSO fidelity, leading to tissue dysplasia and causing several diseases such as microcephaly, dwarfism, and cancer. Whether th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gambarotto, Davide, Pennetier, Carole, Ryniawec, John M., Buster, Daniel W., Gogendeau, Delphine, Goupil, Alix, Nano, Maddalena, Simon, Anthony, Blanc, Damien, Racine, Victor, Kimata, Yuu, Rogers, Gregory C., Basto, Renata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614718/ https://www.ncbi.nlm.nih.gov/pubmed/31130353 http://dx.doi.org/10.1016/j.devcel.2019.04.036

Ejemplares similares

Chromosomes function as a barrier to mitotic spindle bipolarity in polyploid cells
por: Goupil, Alix, et al.
Publicado: (2020)

Moesin Is a Major Regulator of Centrosome Behavior in Epithelial Cells with Extra Centrosomes
por: Sabino, Dora, et al.
Publicado: (2015)

Aneuploidy causes premature differentiation of neural and intestinal stem cells
por: Gogendeau, Delphine, et al.
Publicado: (2015)

An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly
por: McLamarrah, Tiffany A., et al.
Publicado: (2018)

Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles
por: Coelho, Paula A., et al.
Publicado: (2013)

Bug22 influences cilium morphology and the post-translational modification of ciliary microtubules
por: Mendes Maia, Teresa, et al.
Publicado: (2014)

The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification
por: Brownlee, Christopher W., et al.
Publicado: (2011)

Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation
por: Shukla, Anil, et al.
Publicado: (2015)

Plk4 triggers autonomous de novo centriole biogenesis and maturation
por: Nabais, Catarina, et al.
Publicado: (2021)

Promotion and Suppression of Centriole Duplication Are Catalytically Coupled through PLK4 to Ensure Centriole Homeostasis
por: Kim, Minhee, et al.
Publicado: (2016)

Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity
por: Vitiello, Elisa, et al.
Publicado: (2019)

Plk4/SAK/ZYG-1 in the regulation of centriole duplication
por: Pearson, Chad G, et al.
Publicado: (2010)

Cep152 interacts with Plk4 and is required for centriole duplication
por: Hatch, Emily M., et al.
Publicado: (2010)

Plk4-dependent phosphorylation of STIL is required for centriole duplication
por: Kratz, Anne-Sophie, et al.
Publicado: (2015)

Role of Polo-like Kinases Plk1 and Plk4 in the Initiation of Centriole Duplication—Impact on Cancer
por: Hoffmann, Ingrid
Publicado: (2022)

Polo-like kinase 4 homodimerization and condensate formation regulate its own protein levels but are not required for centriole assembly
por: Ryniawec, John M., et al.
Publicado: (2023)

The interrelationship between APC/C and Plk1 activities in centriole disengagement
por: Hatano, Toshiyuki, et al.
Publicado: (2012)

The PLK4–STIL–SAS-6 module at the core of centriole duplication
por: Arquint, Christian, et al.
Publicado: (2016)

Self-organization of Plk4 regulates symmetry breaking in centriole duplication
por: Yamamoto, Shohei, et al.
Publicado: (2019)

Centriole number and the reproductive capacity of spindle poles
Publicado: (1985)

Balancing the scales: fine-tuning Polo-like kinase 4 to ensure proper centriole duplication
por: Ryniawec, John M., et al.
Publicado: (2022)

Molecular Basis for Unidirectional Scaffold Switching of Human Plk4 in Centriole Biogenesis
por: Park, Suk-Youl, et al.
Publicado: (2014)

STIL binding to Polo-box 3 of PLK4 regulates centriole duplication
por: Arquint, Christian, et al.
Publicado: (2015)

Binding of STIL to Plk4 activates kinase activity to promote centriole assembly
por: Moyer, Tyler C., et al.
Publicado: (2015)

A self-assembled cylindrical platform for Plk4-induced centriole biogenesis
por: Lee, Kyung S., et al.
Publicado: (2020)

Transmission ratio distortion of mutations in the master regulator of centriole biogenesis PLK4
por: Neitzel, Heidemarie, et al.
Publicado: (2022)

Overexpressing Centriole-Replication Proteins In Vivo Induces Centriole Overduplication and De Novo Formation
por: Peel, Nina, et al.
Publicado: (2007)

A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4
por: Galletta, Brian J., et al.
Publicado: (2016)

PLK4-phosphorylated NEDD1 facilitates cartwheel assembly and centriole biogenesis initiations
por: Chi, Wangfei, et al.
Publicado: (2020)

PLK4 drives centriole amplification and apical surface area expansion in multiciliated cells
por: LoMastro, Gina M, et al.
Publicado: (2022)

Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles
por: Klena, Nikolai, et al.
Publicado: (2018)

Evolutionary conservation of centriole rotational asymmetry in the human centrosome
por: Gaudin, Noémie, et al.
Publicado: (2022)

Ribonucleoprotein staining of centrioles and kinetochores in newt lung cell spindles
Publicado: (1979)

Fast and furious . . . or not, Plk4 dictates the pace
por: Gemble, Simon, et al.
Publicado: (2018)

CDK11(p58) Is Required for Centriole Duplication and Plk4 Recruitment to Mitotic Centrosomes
por: Franck, Nathalie, et al.
Publicado: (2011)

The SCF(Slimb) ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication
por: Rogers, Gregory C., et al.
Publicado: (2009)

Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles
por: Kong, Dong, et al.
Publicado: (2014)

PLK1 regulation of PCNT cleavage ensures fidelity of centriole separation during mitotic exit
por: Kim, Jaeyoun, et al.
Publicado: (2015)

Autoamplification and Competition Drive Symmetry Breaking: Initiation of Centriole Duplication by the PLK4-STIL Network
por: Leda, Marcin, et al.
Publicado: (2018)

PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole cartwheel to the microtubule wall
por: Moyer, Tyler Chistopher, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_csnj0fnvpsj5ti3jaaetf33eld