mEAK-7 Forms an Alternative mTOR Complex with DNA-PKcs in Human Cancer

MTOR associated protein, eak-7 homolog (mEAK-7), activates mechanistic target of rapamycin (mTOR) signaling in human cells through an alternative mTOR complex to regulate S6K2 and 4E-BP1. However, the role of mEAK-7 in human cancer has not yet been identified. We demonstrate that mEAK-7 and mTOR sig...

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Detalles Bibliográficos
Autores principales: Nguyen, Joe Truong, Haidar, Fatima Sarah, Fox, Alexandra Lucienne, Ray, Connor, Mendonça, Daniela Baccelli, Kim, Jin Koo, Krebsbach, Paul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614755/
https://www.ncbi.nlm.nih.gov/pubmed/31288154
http://dx.doi.org/10.1016/j.isci.2019.06.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614755/
https://www.ncbi.nlm.nih.gov/pubmed/31288154
http://dx.doi.org/10.1016/j.isci.2019.06.029

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