Effect of exercise therapy on physical performance and functional balance in patients on maintenance renal hemodialysis: randomized controlled study

Physical performance (PP) and functional balance (FB) abnormalities are frequently encountered problems in patients on maintenance renal hemodialysis (MRH). Although the exercise therapy is an adjunctive to the routine medical care for patients with chronic kidney disease of various stages; but the benefits as well as the long-term effects of different exercises on the PP and FB in patients on MRH are not yet fully described. In this study; Sixty-six patients on MRH (36 males, 30 females), age 35–45 years, were randomly assigned into one of the three groups: aerobic exercise training group (AETG), resistance exercise training group (RETG), and control group (CG). The PP (evaluated using the 6-min walk test “6MWT”) and the FB (evaluated via the Berg balance scale “BBS”) were the main study outcomes evaluated prestudy (evaluation-1), after 3 months (evaluation-2) and 2 months poststudy cessation (evaluation-3). Results revealed that the PP and FB mean values and percentages of changes at evaluation-2 were 444.25±21.83 (33.1%), 413.57±28.55 (22.52%), 337±12.23 (0.33%) m, 50.05±0.89 (22.95%), 49.95±2.06 (22.52%), 41.28±1.75 (0.94%) for AETG, RETG, and CG respectively. At evaluation-3; the PP and FB mean values and the percentage of changes were 425±21.49 (27.36), 366.86±17.47 (8.5%), 336.68 (0.42%) m, 44.4±1.85 (8.06%), 42.95±2.04 (5.003%), 39.48±2.06 (−4.44%) for AETG, RETG, and CG respectively. In conclusions; both aerobic exercise training (AET) and resistance exercise training (RET) have favorable effects, with the AET has higher short and long-term favorable effects on the PP and FB than RET in patients on MRH.