Multiplexed and tunable transcriptional activation by promoter insertion using nuclease-assisted vector integration

The ability to selectively regulate expression of any target gene within a genome provides a means to address a variety of diseases and disorders. While artificial transcription factors are emerging as powerful tools for gene activation within a natural chromosomal context, current generations often...

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Detalles Bibliográficos
Autores principales: Brown, Alexander, Winter, Jackson, Gapinske, Michael, Tague, Nathan, Woods, Wendy S, Perez-Pinera, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614798/
https://www.ncbi.nlm.nih.gov/pubmed/30931472
http://dx.doi.org/10.1093/nar/gkz210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614798/
https://www.ncbi.nlm.nih.gov/pubmed/30931472
http://dx.doi.org/10.1093/nar/gkz210

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