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Multiplexed and tunable transcriptional activation by promoter insertion using nuclease-assisted vector integration
The ability to selectively regulate expression of any target gene within a genome provides a means to address a variety of diseases and disorders. While artificial transcription factors are emerging as powerful tools for gene activation within a natural chromosomal context, current generations often...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614798/ https://www.ncbi.nlm.nih.gov/pubmed/30931472 http://dx.doi.org/10.1093/nar/gkz210 |