Rouse model with transient intramolecular contacts on a timescale of seconds recapitulates folding and fluctuation of yeast chromosomes

DNA folding and dynamics along with major nuclear functions are determined by chromosome structural properties, which remain, thus far, elusive in vivo. Here, we combine polymer modeling and single particle tracking experiments to determine the physico-chemical parameters of chromatin in vitro and i...

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Detalles Bibliográficos
Autores principales: Socol, Marius, Wang, Renjie, Jost, Daniel, Carrivain, Pascal, Vaillant, Cédric, Le Cam, Eric, Dahirel, Vincent, Normand, Christophe, Bystricky, Kerstin, Victor, Jean-Marc, Gadal, Olivier, Bancaud, Aurélien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614813/
https://www.ncbi.nlm.nih.gov/pubmed/31114898
http://dx.doi.org/10.1093/nar/gkz374

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