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Conformational communication mediates the reset step in t(6)A biosynthesis

The universally conserved N(6)-threonylcarbamoyladenosine (t(6)A) modification of tRNA is essential for translational fidelity. In bacteria, t(6)A biosynthesis starts with the TsaC/TsaC2-catalyzed synthesis of the intermediate threonylcarbamoyl adenylate (TC–AMP), followed by transfer of the threony...

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Detalles Bibliográficos
Autores principales:	Luthra, Amit, Paranagama, Naduni, Swinehart, William, Bayooz, Susan, Phan, Phuc, Quach, Vanessa, Schiffer, Jamie M, Stec, Boguslaw, Iwata-Reuyl, Dirk, Swairjo, Manal A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614819/ https://www.ncbi.nlm.nih.gov/pubmed/31114923 http://dx.doi.org/10.1093/nar/gkz439

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