Cargando…
Thermodynamically stable and genetically unstable G-quadruplexes are depleted in genomes across species
G-quadruplexes play various roles in multiple biological processes, which can be positive when a G4 is involved in the regulation of gene expression or detrimental when the folding of a stable G4 impairs DNA replication promoting genome instability. This duality interrogates the significance of thei...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614823/ https://www.ncbi.nlm.nih.gov/pubmed/31114920 http://dx.doi.org/10.1093/nar/gkz463 |