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DNA barcodes for rapid, whole genome, single-molecule analyses

We report an approach for visualizing DNA sequence and using these ‘DNA barcodes’ to search complex mixtures of genomic material for DNA molecules of interest. We demonstrate three applications of this methodology; identifying specific molecules of interest from a dataset containing gigabasepairs of...

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Detalles Bibliográficos
Autores principales: Wand, Nathaniel O, Smith, Darren A, Wilkinson, Andrew A, Rushton, Ashleigh E, Busby, Stephen J W, Styles, Iain B, Neely, Robert K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614835/
https://www.ncbi.nlm.nih.gov/pubmed/30918971
http://dx.doi.org/10.1093/nar/gkz212