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Single-molecule live cell imaging of Rep reveals the dynamic interplay between an accessory replicative helicase and the replisome

DNA replication must cope with nucleoprotein barriers that impair efficient replisome translocation. Biochemical and genetic studies indicate accessory helicases play essential roles in replication in the presence of nucleoprotein barriers, but how they operate inside the cell is unclear. With high-...

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Detalles Bibliográficos
Autores principales:	Syeda, Aisha H, Wollman, Adam J M, Hargreaves, Alex L, Howard, Jamieson A L, Brüning, Jan-Gert, McGlynn, Peter, Leake, Mark C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614839/ https://www.ncbi.nlm.nih.gov/pubmed/31028385 http://dx.doi.org/10.1093/nar/gkz298

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