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Unprecedented tunability of riboswitch structure and regulatory function by sub-millimolar variations in physiological Mg(2+)
Riboswitches are cis-acting regulatory RNA biosensors that rival the efficiency of those found in proteins. At the heart of their regulatory function is the formation of a highly specific aptamer–ligand complex. Understanding how these RNAs recognize the ligand to regulate gene expression at physiol...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614840/ https://www.ncbi.nlm.nih.gov/pubmed/31045204 http://dx.doi.org/10.1093/nar/gkz316 |