Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing

Chromatin organization and epigenetic markers influence splicing, though the magnitudes of these effects and the mechanisms are largely unknown. Here, we demonstrate that linker histone H1.5 influences mRNA splicing. We observed that linker histone H1.5 binds DNA over splice sites of short exons in...

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Detalles Bibliográficos
Autores principales: Glaich, Ohad, Leader, Yodfat, Lev Maor, Galit, Ast, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614845/
https://www.ncbi.nlm.nih.gov/pubmed/31076740
http://dx.doi.org/10.1093/nar/gkz338

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