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Involvement of inflammasome activation via elevation of uric acid level in nociception in a mouse model of muscle pain

Muscle pain is a common condition in many diseases and is induced by muscle overuse. Muscle overuse induces an increase in uric acid, which stimulates the nucleotide-binding oligomerization domain-like receptor (NLR). This receptor contains the pyrin domain NLRP-3 inflammasome which when activated,...

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Detalles Bibliográficos
Autores principales: Yoshida, Shinichirou, Hagiwara, Yoshihiro, Tsuchiya, Masahiro, Shinoda, Masamichi, Koide, Masashi, Hatakeyama, Hiroyasu, Chaweewannakorn, Chayanit, Suzuki, Kazuaki, Yano, Toshihisa, Sogi, Yasuhito, Itaya, Nobuyuki, Sekiguchi, Takuya, Yabe, Yutaka, Sasaki, Keiichi, Kanzaki, Makoto, Itoi, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614954/
https://www.ncbi.nlm.nih.gov/pubmed/31161887
http://dx.doi.org/10.1177/1744806919858797