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Pituitary Hyperplasia in Severe Primary Hypothyroidism: A Case Report and Review of the Literature

Pituitary hyperplasia is commonly present but remains largely undiagnosed in primary hypothyroidism. It is easily reversible with thyroid replacement therapy. If imaging is performed prior to biochemical evaluation, then patients may undergo pituitary surgery. We present the case of a 34-year-old fe...

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Detalles Bibliográficos
Autores principales: Shukla, Prateek, Bulsara, Ketan R., Luthra, Pooja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614958/
https://www.ncbi.nlm.nih.gov/pubmed/31341683
http://dx.doi.org/10.1155/2019/2012546
Descripción
Sumario:Pituitary hyperplasia is commonly present but remains largely undiagnosed in primary hypothyroidism. It is easily reversible with thyroid replacement therapy. If imaging is performed prior to biochemical evaluation, then patients may undergo pituitary surgery. We present the case of a 34-year-old female with profound primary hypothyroidism and secondary pituitary hyperplasia that resolved after thyroid hormone supplementation. We will discuss the current literature regarding pituitary hyperplasia in primary hypothyroidism in adults.