Completely resolved advanced biliary tract cancer after treatment by pembrolizumab: a report of two cases

Biliary tract cancers (BTC) represent an aggressive disease with a dismal prognosis. Gemcitabine in combination with cisplatin is the standard first-line palliative treatment for advanced BTC. There is no established treatment following progression on gemcitabine-cisplatin. In this article, we prese...

Descripción completa

Detalles Bibliográficos
Autores principales: Alshari, Osama M, Dawaymeh, Tamara A, Tashtush, Nour A, Aleshawi, Abdelwahab J, Al Manasra, Abdel Rahman A, Obeidat, Khaled A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615017/
https://www.ncbi.nlm.nih.gov/pubmed/31308699
http://dx.doi.org/10.2147/OTT.S197559
Descripción
Sumario:Biliary tract cancers (BTC) represent an aggressive disease with a dismal prognosis. Gemcitabine in combination with cisplatin is the standard first-line palliative treatment for advanced BTC. There is no established treatment following progression on gemcitabine-cisplatin. In this article, we present two cases for individuals with advanced BTC who were treated with pembrolizumab and the tumors have completely resolved.

Ejemplares similares