Cargando…
Long non-coding RNA MEG3 inhibits cervical cancer cell growth by promoting degradation of P-STAT3 protein via ubiquitination
BACKGROUND: Maternally expressed 3 (MEG3) plays an important role in cervical cancer development, but its exact role remains unclear. Here, we explored the specific regulatory mechanism of MEG3 and its downstream proteins in cervical cancer cells. METHODS: The effect of MEG3 on tumor formation abili...
Autores principales: | Zhang, Jun, Gao, Yali |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615085/ https://www.ncbi.nlm.nih.gov/pubmed/31320837 http://dx.doi.org/10.1186/s12935-019-0893-z |
Ejemplares similares
-
DNMT1 facilitates growth of breast cancer by inducing MEG3 hyper-methylation
por: Zhu, Xiaotao, et al.
Publicado: (2022) -
Long non-coding RNA DANCR promotes cervical cancer growth via activation of the Wnt/β-catenin signaling pathway
por: Tian, Wanjia, et al.
Publicado: (2020) -
LncRNA MEG3 promotes melanoma growth, metastasis and formation through modulating miR-21/E-cadherin axis
por: Wu, Liangcai, et al.
Publicado: (2020) -
NEDD4L-induced ubiquitination mediating UBE2T degradation inhibits progression of lung adenocarcinoma via PI3K-AKT signaling
por: Chen, Yongbing, et al.
Publicado: (2021) -
Eupalinolide J Inhibits Cancer Metastasis by Promoting STAT3 Ubiquitin-Dependent Degradation
por: Hu, Hongtao, et al.
Publicado: (2023)