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Mitochondrial DNA: the overlooked oncogenome?

Perturbed mitochondrial bioenergetics constitute a core pillar of cancer-associated metabolic dysfunction. While mitochondrial dysfunction in cancer may result from myriad biochemical causes, a historically neglected source is that of the mitochondrial genome. Recent large-scale sequencing efforts a...

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Detalles Bibliográficos
Autores principales: Gammage, Payam A., Frezza, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615100/
https://www.ncbi.nlm.nih.gov/pubmed/31286943
http://dx.doi.org/10.1186/s12915-019-0668-y

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