Reference genome and comparative genome analysis for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine

BACKGROUND: Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). In an effort to standardize the vaccine production, three substrains, i.e. BCG Danish 1331, Tokyo 172–1 and Russia BCG-1 were established as the WHO reference strains. Bot...

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Detalles Bibliográficos
Autores principales: Borgers, Katlyn, Ou, Jheng-Yang, Zheng, Po-Xing, Tiels, Petra, Van Hecke, Annelies, Plets, Evelyn, Michielsen, Gitte, Festjens, Nele, Callewaert, Nico, Lin, Yao-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615170/
https://www.ncbi.nlm.nih.gov/pubmed/31286858
http://dx.doi.org/10.1186/s12864-019-5909-5

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