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TGFβ1 is essential for MSCs-CAFs differentiation and promotes HCT116 cells migration and invasion via JAK/STAT3 signaling

BACKGROUND AND PURPOSE: Colorectal cancer (CRC) frequently metastasizes to the liver, which involves the participation of multiple cytokines. Tumor microenvironment (TME) composed of cancer-associated fibroblasts (CAFs) and tumor cells acts as an essential factor in cancer metastasis. Transforming g...

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Detalles Bibliográficos
Autores principales:	Tan, Hao-Xiang, Cao, Zhen-Bin, He, Ting-Ting, Huang, Tao, Xiang, Cai-Ling, Liu, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615717/ https://www.ncbi.nlm.nih.gov/pubmed/31308702 http://dx.doi.org/10.2147/OTT.S178618

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