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Mésusage des dermocorticoïdes: une image vaut mille mots
Dermocorticoids (DC) are the first line treatment for mild to moderate psoriasis. Despite their relative safety, long-term use and most of all self-medication practice could expose them to a risk of skin atrophy. We report the case of a 50-year old female patient, treated for psoriasis with chronic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615770/ https://www.ncbi.nlm.nih.gov/pubmed/31312340 http://dx.doi.org/10.11604/pamj.2019.33.24.18273 |
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author | Houssaini, Asmaa Sqalli Hassam, Badreddine |
author_facet | Houssaini, Asmaa Sqalli Hassam, Badreddine |
author_sort | Houssaini, Asmaa Sqalli |
collection | PubMed |
description | Dermocorticoids (DC) are the first line treatment for mild to moderate psoriasis. Despite their relative safety, long-term use and most of all self-medication practice could expose them to a risk of skin atrophy. We report the case of a 50-year old female patient, treated for psoriasis with chronic application of topical dermocorticoids over several years. Her skin appeared to be very thin, displaying the underlying venous network, telangiectasias as well as stretch marks which are manifestations of dermo-epidermal atrophy. Skin atrophy is the most common adverse effect of dermocorticoids and it is due to their strong antiproliferative effect on keratinocytes, melanocytes and fibroblasts which synthesize the collagen. It may be associated with delayed wound healing and various infectious complications; hence the importance of providing proper patient education. |
format | Online Article Text |
id | pubmed-6615770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-66157702019-07-16 Mésusage des dermocorticoïdes: une image vaut mille mots Houssaini, Asmaa Sqalli Hassam, Badreddine Pan Afr Med J Images in Medicine Dermocorticoids (DC) are the first line treatment for mild to moderate psoriasis. Despite their relative safety, long-term use and most of all self-medication practice could expose them to a risk of skin atrophy. We report the case of a 50-year old female patient, treated for psoriasis with chronic application of topical dermocorticoids over several years. Her skin appeared to be very thin, displaying the underlying venous network, telangiectasias as well as stretch marks which are manifestations of dermo-epidermal atrophy. Skin atrophy is the most common adverse effect of dermocorticoids and it is due to their strong antiproliferative effect on keratinocytes, melanocytes and fibroblasts which synthesize the collagen. It may be associated with delayed wound healing and various infectious complications; hence the importance of providing proper patient education. The African Field Epidemiology Network 2019-05-14 /pmc/articles/PMC6615770/ /pubmed/31312340 http://dx.doi.org/10.11604/pamj.2019.33.24.18273 Text en © Asmaa Sqalli Houssaini et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Images in Medicine Houssaini, Asmaa Sqalli Hassam, Badreddine Mésusage des dermocorticoïdes: une image vaut mille mots |
title | Mésusage des dermocorticoïdes: une image vaut mille mots |
title_full | Mésusage des dermocorticoïdes: une image vaut mille mots |
title_fullStr | Mésusage des dermocorticoïdes: une image vaut mille mots |
title_full_unstemmed | Mésusage des dermocorticoïdes: une image vaut mille mots |
title_short | Mésusage des dermocorticoïdes: une image vaut mille mots |
title_sort | mésusage des dermocorticoïdes: une image vaut mille mots |
topic | Images in Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615770/ https://www.ncbi.nlm.nih.gov/pubmed/31312340 http://dx.doi.org/10.11604/pamj.2019.33.24.18273 |
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