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RAIN study: a protocol for a randomised controlled trial evaluating efficacy, safety and cost-effectiveness of intravenous-to-oral antibiotic switch therapy in neonates with a probable bacterial infection
INTRODUCTION: High morbidity and mortality rates of proven bacterial infection are the main reason for substantial use of intravenous antibiotics in neonates during the first week of life. In older children, intravenous-to-oral switch after 48 hours of intravenous therapy has been shown to have many...
Autores principales: | Keij, Fleur M, Kornelisse, René F, Hartwig, Nico G, Mauff, Katya, Poley, Marten J, Allegaert, Karel, Reiss, Irwin K M, Tramper-Stranders, Gerdien A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615779/ https://www.ncbi.nlm.nih.gov/pubmed/31289068 http://dx.doi.org/10.1136/bmjopen-2018-026688 |
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