Assessing the safety and pharmacokinetics of the monoclonal antibodies, VRC07-523LS and PGT121 in HIV negative women in South Africa: study protocol for the CAPRISA 012A randomised controlled phase I trial

INTRODUCTION: Despite extensive prevention campaigns and scale-up of antiretroviral therapy, HIV incidence among young women in southern Africa remains high. While the development of an efficacious vaccine remains a challenge, the discovery of broadly neutralising monoclonal antibodies (mAbs) has cr...

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Detalles Bibliográficos
Autores principales: Mahomed, Sharana, Garrett, Nigel, Capparelli, Edmund, Baxter, Cheryl, Zuma, Nonhlanhla Yende, Gengiah, Tanuja, Archary, Derseree, Moore, Penny, Samsunder, Natasha, Barouch, Dan H, Mascola, John, Ledgerwood, Julie, Morris, Lynn, Abdool Karim, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
HIV/AIDS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615816/
https://www.ncbi.nlm.nih.gov/pubmed/31272988
http://dx.doi.org/10.1136/bmjopen-2019-030283

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