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Genetic interactions of G-quadruplexes in humans

G-quadruplexes (G4) are alternative nucleic acid structures involved in transcription, translation and replication. Aberrant G4 formation and stabilisation is linked to genome instability and cancer. G4 ligand treatment disrupts key biological processes leading to cell death. To discover genes and p...

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Detalles Bibliográficos
Autores principales:	Zyner, Katherine G, Mulhearn, Darcie S, Adhikari, Santosh, Martínez Cuesta, Sergio, Di Antonio, Marco, Erard, Nicolas, Hannon, Gregory J, Tannahill, David, Balasubramanian, Shankar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615864/ https://www.ncbi.nlm.nih.gov/pubmed/31287417 http://dx.doi.org/10.7554/eLife.46793

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