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Genetic interactions of G-quadruplexes in humans
G-quadruplexes (G4) are alternative nucleic acid structures involved in transcription, translation and replication. Aberrant G4 formation and stabilisation is linked to genome instability and cancer. G4 ligand treatment disrupts key biological processes leading to cell death. To discover genes and p...
Autores principales: | Zyner, Katherine G, Mulhearn, Darcie S, Adhikari, Santosh, Martínez Cuesta, Sergio, Di Antonio, Marco, Erard, Nicolas, Hannon, Gregory J, Tannahill, David, Balasubramanian, Shankar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615864/ https://www.ncbi.nlm.nih.gov/pubmed/31287417 http://dx.doi.org/10.7554/eLife.46793 |
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