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Identifying, understanding, and correcting technical artifacts on the sex chromosomes in next-generation sequencing data
BACKGROUND: Mammalian X and Y chromosomes share a common evolutionary origin and retain regions of high sequence similarity. Similar sequence content can confound the mapping of short next-generation sequencing reads to a reference genome. It is therefore possible that the presence of both sex chrom...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615978/ https://www.ncbi.nlm.nih.gov/pubmed/31289836 http://dx.doi.org/10.1093/gigascience/giz074 |