Severe Infantile Bullous Pemphigoid Treated with Dapsone after Bridging with Systemic Glucocorticoid

We present a case of severe and treatment-refractory bullous pemphigoid in a 3-month-old child. After topical and systemic corticoid treatment proved inefficient, dapsone 0.75 mg/kg was added initially without success. Disease control was reached with dapsone 1.5 mg/kg in addition to both topical an...

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Detalles Bibliográficos
Autores principales: Thomsen, Kenneth, Deleuran, Mette, Vestergaard, Christian, Holm, Mette, Riber-Hansen, Rikke, Bech, Rikke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616048/
https://www.ncbi.nlm.nih.gov/pubmed/31320867
http://dx.doi.org/10.1159/000501359
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author Thomsen, Kenneth
Deleuran, Mette
Vestergaard, Christian
Holm, Mette
Riber-Hansen, Rikke
Bech, Rikke
author_facet Thomsen, Kenneth
Deleuran, Mette
Vestergaard, Christian
Holm, Mette
Riber-Hansen, Rikke
Bech, Rikke
author_sort Thomsen, Kenneth
collection PubMed
description We present a case of severe and treatment-refractory bullous pemphigoid in a 3-month-old child. After topical and systemic corticoid treatment proved inefficient, dapsone 0.75 mg/kg was added initially without success. Disease control was reached with dapsone 1.5 mg/kg in addition to both topical and systemic glucocorticoid treatment, leaving the child with several side effects of the glucocorticoid treatment.
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spelling pubmed-66160482019-07-18 Severe Infantile Bullous Pemphigoid Treated with Dapsone after Bridging with Systemic Glucocorticoid Thomsen, Kenneth Deleuran, Mette Vestergaard, Christian Holm, Mette Riber-Hansen, Rikke Bech, Rikke Case Rep Dermatol Single Case We present a case of severe and treatment-refractory bullous pemphigoid in a 3-month-old child. After topical and systemic corticoid treatment proved inefficient, dapsone 0.75 mg/kg was added initially without success. Disease control was reached with dapsone 1.5 mg/kg in addition to both topical and systemic glucocorticoid treatment, leaving the child with several side effects of the glucocorticoid treatment. S. Karger AG 2019-06-26 /pmc/articles/PMC6616048/ /pubmed/31320867 http://dx.doi.org/10.1159/000501359 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Thomsen, Kenneth
Deleuran, Mette
Vestergaard, Christian
Holm, Mette
Riber-Hansen, Rikke
Bech, Rikke
Severe Infantile Bullous Pemphigoid Treated with Dapsone after Bridging with Systemic Glucocorticoid
title Severe Infantile Bullous Pemphigoid Treated with Dapsone after Bridging with Systemic Glucocorticoid
title_full Severe Infantile Bullous Pemphigoid Treated with Dapsone after Bridging with Systemic Glucocorticoid
title_fullStr Severe Infantile Bullous Pemphigoid Treated with Dapsone after Bridging with Systemic Glucocorticoid
title_full_unstemmed Severe Infantile Bullous Pemphigoid Treated with Dapsone after Bridging with Systemic Glucocorticoid
title_short Severe Infantile Bullous Pemphigoid Treated with Dapsone after Bridging with Systemic Glucocorticoid
title_sort severe infantile bullous pemphigoid treated with dapsone after bridging with systemic glucocorticoid
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616048/
https://www.ncbi.nlm.nih.gov/pubmed/31320867
http://dx.doi.org/10.1159/000501359
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