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Defects in COG-Mediated Golgi Trafficking Alter Endo-Lysosomal System in Human Cells

The conserved oligomeric complex (COG) is a multi-subunit vesicle tethering complex that functions in retrograde trafficking at the Golgi. We have previously demonstrated that the formation of enlarged endo-lysosomal structures (EELSs) is one of the major glycosylation-independent phenotypes of cell...

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Detalles Bibliográficos
Autores principales:	D’Souza, Zinia, Blackburn, Jessica Bailey, Kudlyk, Tetyana, Pokrovskaya, Irina D., Lupashin, Vladimir V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616090/ https://www.ncbi.nlm.nih.gov/pubmed/31334232 http://dx.doi.org/10.3389/fcell.2019.00118

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