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Pharmacokinetic Modeling of Targeted Ultrasound Contrast Agents for Quantitative Assessment of Anti-Angiogenic Therapy: a Longitudinal Case-Control Study in Colon Cancer

PURPOSE: To evaluate quantitative and semi-quantitative ultrasound molecular imaging (USMI) for antiangiogenic therapy monitoring in human colon cancer xenografts in mice. PROCEDURES: Colon cancer was established in 17 mice by injection of LS174T (N(r) = 9) or CT26 (N(n) = 8) cancer cells to simulat...

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Detalles Bibliográficos
Autores principales: Turco, Simona, El Kaffas, Ahmed, Zhou, Jianhua, Lutz, Amelie M., Wijkstra, Hessel, Willmann, Jürgen K., Mischi, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616210/
https://www.ncbi.nlm.nih.gov/pubmed/30225758
http://dx.doi.org/10.1007/s11307-018-1274-z