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Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery

The aim of this study was to assess the central macular imaging captured with an optical biometer based on full-eye-length Swept-Source OCT (SS-OCT) scan as a screening strategy for identifying macular diseases in patients scheduled for cataract surgery. 1,114 eyes of 749 consecutive patients underw...

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Autores principales: Tognetto, Daniele, Pastore, Marco R., De Giacinto, Chiara, Merli, Riccardo, Franzon, Marco, D’Aloisio, Rossella, Belfanti, Lorenzo, Giglio, Rosa, Cirigliano, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616355/
https://www.ncbi.nlm.nih.gov/pubmed/31289313
http://dx.doi.org/10.1038/s41598-019-46243-3
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author Tognetto, Daniele
Pastore, Marco R.
De Giacinto, Chiara
Merli, Riccardo
Franzon, Marco
D’Aloisio, Rossella
Belfanti, Lorenzo
Giglio, Rosa
Cirigliano, Gabriella
author_facet Tognetto, Daniele
Pastore, Marco R.
De Giacinto, Chiara
Merli, Riccardo
Franzon, Marco
D’Aloisio, Rossella
Belfanti, Lorenzo
Giglio, Rosa
Cirigliano, Gabriella
author_sort Tognetto, Daniele
collection PubMed
description The aim of this study was to assess the central macular imaging captured with an optical biometer based on full-eye-length Swept-Source OCT (SS-OCT) scan as a screening strategy for identifying macular diseases in patients scheduled for cataract surgery. 1,114 eyes of 749 consecutive patients underwent a biometrical examination with IOLMaster 700 SS-OCT technology (Carl Zeiss) and conventional Spectral-Domain OCT (SD-OCT) (Spectralis OCT, Heidelberg) device analysis on the same day. Seven examiners graded the scans individually in a full-masked mode. Twenty-five eyes were excluded for media opacities. Among the 1,089 included eyes, statistical analysis revealed a mean Kendall’s Coefficient of 0.83 (range 0.76–0.89). A logistic regression model demonstrated a highly significant correlation (p < 0.001) between the coefficient of concordance and SD-OCT imaging. Intraobserver reproducibility was 0.89 (range 0.86–0.91). Optical biometer SS-OCT scans showed a mean sensitivity of 0.81 and a mean specificity of 0.84. The positive and negative predictive value detected was 0.78 and 0.86, respectively. In order to predict the risk of reduced visual recovery, especially in cases of retinal pathology, optical biometer with SS-OCT scan has proven to be a useful modality for detecting macular structural abnormalities in patients undergoing cataract surgery. Conventional SD-OCT remains mandatory to confirm the presumed diagnosis.
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spelling pubmed-66163552019-07-18 Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery Tognetto, Daniele Pastore, Marco R. De Giacinto, Chiara Merli, Riccardo Franzon, Marco D’Aloisio, Rossella Belfanti, Lorenzo Giglio, Rosa Cirigliano, Gabriella Sci Rep Article The aim of this study was to assess the central macular imaging captured with an optical biometer based on full-eye-length Swept-Source OCT (SS-OCT) scan as a screening strategy for identifying macular diseases in patients scheduled for cataract surgery. 1,114 eyes of 749 consecutive patients underwent a biometrical examination with IOLMaster 700 SS-OCT technology (Carl Zeiss) and conventional Spectral-Domain OCT (SD-OCT) (Spectralis OCT, Heidelberg) device analysis on the same day. Seven examiners graded the scans individually in a full-masked mode. Twenty-five eyes were excluded for media opacities. Among the 1,089 included eyes, statistical analysis revealed a mean Kendall’s Coefficient of 0.83 (range 0.76–0.89). A logistic regression model demonstrated a highly significant correlation (p < 0.001) between the coefficient of concordance and SD-OCT imaging. Intraobserver reproducibility was 0.89 (range 0.86–0.91). Optical biometer SS-OCT scans showed a mean sensitivity of 0.81 and a mean specificity of 0.84. The positive and negative predictive value detected was 0.78 and 0.86, respectively. In order to predict the risk of reduced visual recovery, especially in cases of retinal pathology, optical biometer with SS-OCT scan has proven to be a useful modality for detecting macular structural abnormalities in patients undergoing cataract surgery. Conventional SD-OCT remains mandatory to confirm the presumed diagnosis. Nature Publishing Group UK 2019-07-09 /pmc/articles/PMC6616355/ /pubmed/31289313 http://dx.doi.org/10.1038/s41598-019-46243-3 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Tognetto, Daniele
Pastore, Marco R.
De Giacinto, Chiara
Merli, Riccardo
Franzon, Marco
D’Aloisio, Rossella
Belfanti, Lorenzo
Giglio, Rosa
Cirigliano, Gabriella
Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery
title Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery
title_full Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery
title_fullStr Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery
title_full_unstemmed Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery
title_short Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery
title_sort swept-source optical coherence tomography biometer as screening strategy for macular disease in patients scheduled for cataract surgery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616355/
https://www.ncbi.nlm.nih.gov/pubmed/31289313
http://dx.doi.org/10.1038/s41598-019-46243-3
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