Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells

The GM3(Neu5Gc) ganglioside represents a tumor-specific antigen that is considered a promising target for cancer immunotherapy. We previously demonstrated that the humanized antibody 14F7hT, specific for this ganglioside, exhibited significant antitumor effects in preclinical hematological tumor mod...

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Detalles Bibliográficos
Autores principales: Dorvignit, Denise, Boligan, Kayluz F., Relova-Hernández, Ernesto, Clavell, Marilyn, López, Armando, Labrada, Mayrel, Simon, Hans-Uwe, López-Requena, Alejandro, Mesa, Circe, von Gunten, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616363/
https://www.ncbi.nlm.nih.gov/pubmed/31289278
http://dx.doi.org/10.1038/s41598-019-46148-1

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