Cargando…

Mitochondrial Akt Signaling Modulated Reprogramming of Somatic Cells

The signaling mechanisms controlling somatic cell reprogramming are not fully understood. In this study, we report a novel role for mitochondrial Akt1 signaling that enhanced somatic cell reprogramming efficiency. The role of mitochondrial Akt1 in somatic cell reprogramming was investigated by trans...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yu-Han, Su, Ching-Chieh, Deng, Wu, Lock, Leslie F., Donovan, Peter J., Kayala, Matthew A., Baldi, Pierre, Lee, Hsiao-Chen, Chen, Yumay, Wang, Ping H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616364/ https://www.ncbi.nlm.nih.gov/pubmed/31289326 http://dx.doi.org/10.1038/s41598-019-46359-6

Ejemplares similares

Cyber-T web server: differential analysis of high-throughput data
por: Kayala, Matthew A., et al.
Publicado: (2012)

Dual roles of myocardial mitochondrial AKT on diabetic cardiomyopathy and whole body metabolism
por: Chen, Yu-Han, et al.
Publicado: (2023)

PHLDA3 impedes somatic cell reprogramming by activating Akt-GSK3β pathway
por: Qiao, Mengran, et al.
Publicado: (2017)

Metabolic Reprogramming in Response to Alterations of Mitochondrial DNA and Mitochondrial Dysfunction in Gastric Adenocarcinoma
por: Chang, Tzu-Ching, et al.
Publicado: (2022)

Interspecies Somatic Cell Nuclear Transfer Is Dependent on Compatible Mitochondrial DNA and Reprogramming Factors
por: Jiang, Yan, et al.
Publicado: (2011)

Protocols for analysis of mitochondrial permeability transition pore opening in mouse somatic cell reprogramming
por: Ying, Zhongfu, et al.
Publicado: (2021)

Organelle remodeling in somatic cell reprogramming
por: Liu, Yang, et al.
Publicado: (2020)

Somatic Reprogramming—Above and Beyond Pluripotency
por: Meir, Yaa-Jyuhn James, et al.
Publicado: (2021)

The dynamics of chromatin states mediated by epigenetic modifications during somatic cell reprogramming
por: Peng, Jing, et al.
Publicado: (2023)

Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming
por: Tanaka, Yoshiaki, et al.
Publicado: (2015)

MicroRNA-mediated regulation of extracellular matrix formation modulates somatic cell reprogramming
por: Li, Zhonghan, et al.
Publicado: (2014)

Five Classic Articles in Somatic Cell Reprogramming
por: Park, In-Hyun
Publicado: (2010)

JAK-STAT3 and somatic cell reprogramming
por: Tang, Yong, et al.
Publicado: (2013)

Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance
por: Ozmadenci, Duygu, et al.
Publicado: (2015)

Lutein Inhibits the Migration of Retinal Pigment Epithelial Cells via Cytosolic and Mitochondrial Akt Pathways (Lutein Inhibits RPE Cells Migration)
por: Su, Ching-Chieh, et al.
Publicado: (2014)

Extraneous E-Cadherin Engages the Deterministic Process of Somatic Reprogramming through Modulating STAT3 and Erk1/2 Activity
por: Liu, Yu-Hao, et al.
Publicado: (2021)

Serum Starvation Induced Cell Cycle Synchronization Facilitates Human Somatic Cells Reprogramming
por: Chen, Mengfei, et al.
Publicado: (2012)

TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition
por: Wang, Yuan, et al.
Publicado: (2020)

Suppression of the ERK–SRF axis facilitates somatic cell reprogramming
por: Huh, Sejong, et al.
Publicado: (2018)

Sirt6 regulates efficiency of mouse somatic reprogramming and maintenance of pluripotency
por: Xu, Peng, et al.
Publicado: (2019)

Reprogrammed Transcriptome in Rhesus-Bovine Interspecies Somatic Cell Nuclear Transfer Embryos
por: Wang, Kai, et al.
Publicado: (2011)

Application and prospects of somatic cell reprogramming technology for spinal cord injury treatment
por: Yang, Riyun, et al.
Publicado: (2022)

Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells
por: Huang, Kaimeng, et al.
Publicado: (2015)

Proliferation Rate of Somatic Cells Affects Reprogramming Efficiency
por: Xu, Yongyu, et al.
Publicado: (2013)

Nuclear reprogramming of sperm and somatic nuclei in eggs and oocytes
por: Teperek, Marta, et al.
Publicado: (2013)

Optimal Ratio of Transcription Factors for Somatic Cell Reprogramming
por: Nagamatsu, Go, et al.
Publicado: (2012)

A Cell Electrofusion Chip for Somatic Cells Reprogramming
por: Wu, Wei, et al.
Publicado: (2015)

Conserved regulation of RNA processing in somatic cell reprogramming
por: Kanitz, Alexander, et al.
Publicado: (2019)

Mechanisms of the Metabolic Shift during Somatic Cell Reprogramming
por: Nishimura, Ken, et al.
Publicado: (2019)

Mitochondrial Physiology and Gene Expression Analyses Reveal Metabolic and Translational Dysregulation in Oocyte-Induced Somatic Nuclear Reprogramming
por: Esteves, Telma C., et al.
Publicado: (2012)

Reduced expression of Paternally Expressed Gene-3 enhances somatic cell reprogramming through mitochondrial activity perturbation
por: Theka, Ilda, et al.
Publicado: (2017)

Somatic Cell Reprogramming for Nervous System Diseases: Techniques, Mechanisms, Potential Applications, and Challenges
por: Chen, Jiafeng, et al.
Publicado: (2023)

Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells
por: Sarig, Rachel, et al.
Publicado: (2010)

Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming
por: Xi, Chenxiang, et al.
Publicado: (2022)

Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo
por: He, Songwei, et al.
Publicado: (2015)

Correction: Reprogrammed Transcriptome in Rhesus-Bovine Interspecies Somatic Cell Nuclear Transfer Embryos
por: Wang, Kai, et al.
Publicado: (2012)

Epithelial-Mesenchymal Transition and Metabolic Switching in Cancer: Lessons From Somatic Cell Reprogramming
por: Lai, Xiaowei, et al.
Publicado: (2020)

Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: New insight into the role of mitophagy in cell stemness
por: Vazquez-Martin, Alejandro, et al.
Publicado: (2012)

Critical POU domain residues confer Oct4 uniqueness in somatic cell reprogramming
por: Jin, Wensong, et al.
Publicado: (2016)

Characterization of AKT Somatic Mutations in Chinese Breast Cancer Patients
por: Wen, Lingzhu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_diq4i5s73rkfniutr6ouvpnvqq