Cargando…

MicroRNA410 Inhibits Pulmonary Vascular Remodeling via Regulation of Nicotinamide Phosphoribosyltransferase

Nicotinamide phosphoribosyltransferase (NAMPT) upregulation in human pulmonary artery endothelial cells (hPAECs) is associated with pulmonary arterial hypertension (PAH) progression and pulmonary vascular remodeling. The underlying mechanisms regulating NAMPT expression are still not clear. In this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Hui, Chen, Jiwang, Chen, Tianji, Wang, Yifang, Song, Yang, Dong, Yangbasai, Zhao, Shuangping, Machado, Roberto F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616369/ https://www.ncbi.nlm.nih.gov/pubmed/31289307 http://dx.doi.org/10.1038/s41598-019-46352-z

Ejemplares similares

Nicotinamide phosphoribosyltransferase leukocyte overexpression in Graves’ opthalmopathy
por: Sawicka-Gutaj, Nadia, et al.
Publicado: (2016)

Nicotinamide Phosphoribosyltransferase/Visfatin Does Not Catalyze Nicotinamide Mononucleotide Formation in Blood Plasma
por: Hara, Nobumasa, et al.
Publicado: (2011)

MicroRNA-494 induces breast cancer cell apoptosis and reduces cell viability by inhibition of nicotinamide phosphoribosyltransferase expression and activity
por: Ghorbanhosseini, Seyedeh Sara, et al.
Publicado: (2019)

Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine
por: Grolla, Ambra A, et al.
Publicado: (2016)

Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase
por: Zhang, Li Q, et al.
Publicado: (2017)

Prognostic value of serum nicotinamide phosphoribosyltransferase in patients with bladder cancer
por: Zhang, Kui, et al.
Publicado: (2014)

Nicotinamide Phosphoribosyltransferase May Be Involved in Age-Related Brain Diseases
por: Liu, Li-Ying, et al.
Publicado: (2012)

Structural Basis of Beneficial Design for Effective Nicotinamide Phosphoribosyltransferase Inhibitors
por: Tanuma, Sei-ichi, et al.
Publicado: (2020)

Nicotinamide Phosphoribosyltransferase as a Key Molecule of the Aging/Senescence Process
por: Khaidizar, Fiqri D., et al.
Publicado: (2021)

Nicotinamide phosphoribosyltransferase as a biomarker for the diagnosis of infectious pleural effusions
por: Huang, Jing, et al.
Publicado: (2021)

Nicotinamide phosphoribosyltransferase regulates the cell differentiation and mineralization in cultured odontoblasts
por: Kang, Kyeong-Rok, et al.
Publicado: (2022)

Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies
por: Biniecka, Paulina, et al.
Publicado: (2023)

Extracellular nicotinamide phosphoribosyltransferase: role in disease pathophysiology and as a biomarker
por: Semerena, Elise, et al.
Publicado: (2023)

Circular RNA triple functional domain promotes osteoarthritis’ development by modulating the microRNA-136-5p/Nicotinamide phosphoribosyltransferase axis
por: Yang, Jin, et al.
Publicado: (2022)

Nicotinamide phosphoribosyltransferase-related signaling pathway in early Alzheimer's disease mouse models
por: Xing, Sanli, et al.
Publicado: (2019)

Discovery and characterization of novel small-molecule inhibitors targeting nicotinamide phosphoribosyltransferase
por: Xu, Tian-Ying, et al.
Publicado: (2015)

Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody–Drug Conjugates
por: Karpov, Alexei S., et al.
Publicado: (2018)

Clickable prodrugs bearing potent and hydrolytically cleavable nicotinamide phosphoribosyltransferase inhibitors
por: Sadrerafi, Keivan, et al.
Publicado: (2018)

Nicotinamide Phosphoribosyltransferase Attenuates Methotrexate Response in Juvenile Idiopathic Arthritis and In Vitro
por: Funk, RS, et al.
Publicado: (2016)

Epigenetic regulation of Runx2 transcription and osteoblast differentiation by nicotinamide phosphoribosyltransferase
por: Ling, Min, et al.
Publicado: (2017)

Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype
por: Kuehnemann, Chisaka, et al.
Publicado: (2022)

Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase
por: Olesen, Uffe H, et al.
Publicado: (2010)

Metabolomics Analysis of Metabolic Effects of Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibition on Human Cancer Cells
por: Tolstikov, Vladimir, et al.
Publicado: (2014)

MicroRNA-410 Reduces the Expression of Vascular Endothelial Growth Factor and Inhibits Oxygen-Induced Retinal Neovascularization
por: Chen, Na, et al.
Publicado: (2014)

Changes of Nicotinamide Phosphoribosyltransferase Expressions in Thyroid Glands of Patients with Different Thyroid Pathologies
por: Sawicka-Gutaj, Nadia, et al.
Publicado: (2018)

SIRT1 selectively exerts the metabolic protective effects of hepatocyte nicotinamide phosphoribosyltransferase
por: Higgins, Cassandra B., et al.
Publicado: (2022)

Nicotinamide Phosphoribosyltransferase (Nampt)/Nicotinamide Adenine Dinucleotide (NAD) Axis Suppresses Atrial Fibrillation by Modulating the Calcium Handling Pathway
por: Feng, Duo, et al.
Publicado: (2020)

Dezocine, An Opioid Analgesic, Exerts Antitumor Effects in Triple-Negative Breast Cancer by Targeting Nicotinamide Phosphoribosyltransferase
por: Xue, Chenyang, et al.
Publicado: (2021)

Cerebral Ischemia Is Exacerbated by Extracellular Nicotinamide Phosphoribosyltransferase via a Non-Enzymatic Mechanism
por: Zhao, Bing, et al.
Publicado: (2013)

Cross resistance to diverse anticancer nicotinamide phosphoribosyltransferase inhibitors induced by FK866 treatment
por: Ogino, Yoko, et al.
Publicado: (2018)

Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy
por: LoCoco, Peter M, et al.
Publicado: (2017)

Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4
por: Gasparrini, Massimiliano, et al.
Publicado: (2022)

Serum nicotinamide phosphoribosyltransferase as a novel biomarker for non-traumatic osteonecrosis of the femoral head
por: Wang, Shiying, et al.
Publicado: (2022)

Iminosugar-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Potential Anti-Pancreatic Cancer Agents
por: Conforti, Irene, et al.
Publicado: (2023)

Inhibition of Nicotinamide Phosphoribosyltransferase Induces Apoptosis in Estrogen Receptor-Positive MCF-7 Breast Cancer Cells
por: Alaee, Mohammad, et al.
Publicado: (2017)

Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension
por: Ma, Wenrui, et al.
Publicado: (2021)

MicroRNA-410-5p exacerbates high-fat diet-induced cardiac remodeling in mice in an endocrine fashion
por: Zou, Tong, et al.
Publicado: (2018)

Expression of Nicotinamide Phosphoribosyltransferase-Influenced Genes Predicts Recurrence-Free Survival in Lung and Breast Cancers
por: Zhou, Tong, et al.
Publicado: (2014)

Nicotinamide phosphoribosyltransferase expression and clinical outcome of resected stage I/II pancreatic ductal adenocarcinoma
por: Davis, Katelynn, et al.
Publicado: (2019)

Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats
por: Wu, Geng-Chin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ad65icgefb7nuqv4e8jcmq2qt5