AAV-Mediated Expression of Broadly Neutralizing and Vaccine-like Antibodies Targeting the HIV-1 Envelope V2 Region

HIV-1 infection continues to be a global health challenge and a vaccine is urgently needed. Broadly neutralizing antibodies (bNAbs) are considered essential as they inhibit multiple HIV-1 strains, but they are difficult to elicit by conventional immunization. In contrast, non-neutralizing antibodies...

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Detalles Bibliográficos
Autores principales: van den Berg, Fiona T., Makoah, Nigel A., Ali, Stuart A., Scott, Tristan A., Mapengo, Rutendo E., Mutsvunguma, Lorraine Z., Mkhize, Nonhlanhla N., Lambson, Bronwen E., Kgagudi, Prudence D., Crowther, Carol, Abdool Karim, Salim S., Balazs, Alejandro B., Weinberg, Marc S., Ely, Abdullah, Arbuthnot, Patrick B., Morris, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616373/
https://www.ncbi.nlm.nih.gov/pubmed/31334303
http://dx.doi.org/10.1016/j.omtm.2019.06.002

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