Cargando…
Suppression of AMD-Like Pathology by Mitochondria-Targeted Antioxidant SkQ1 Is Associated with a Decrease in the Accumulation of Amyloid β and in mTOR Activity
Age-related macular degeneration (AMD) is a major cause of irreversible visual impairment and blindness in developed countries, and the molecular pathogenesis of AMD is poorly understood. Recent studies strongly indicate that amyloid β (Aβ) accumulation —found in the brain and a defining feature of...
Autores principales: | Muraleva, Natalia A., Kozhevnikova, Oyuna S., Fursova, Anzhela Z., Kolosova, Nataliya G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616484/ https://www.ncbi.nlm.nih.gov/pubmed/31208023 http://dx.doi.org/10.3390/antiox8060177 |
Ejemplares similares
-
The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats
por: Kolosova, Nataliya G., et al.
Publicado: (2012) -
SkQ1 Suppresses the p38 MAPK Signaling Pathway Involved in Alzheimer’s Disease-Like Pathology in OXYS Rats
por: Muraleva, Natalia A., et al.
Publicado: (2020) -
Therapeutic Action of the Mitochondria-Targeted Antioxidant SkQ1 on Retinopathy in OXYS Rats Linked with Improvement of VEGF and PEDF Gene Expression
por: Markovets, Anton M., et al.
Publicado: (2011) -
Mitochondria-targeted antioxidant SkQ1 reduces age-related alterations in the ultrastructure of the lacrimal gland
por: Bakeeva, Lora E., et al.
Publicado: (2016) -
The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy
por: Perepechaeva, M. L., et al.
Publicado: (2014)