Cargando…

Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances

People with Parkinson’s disease (PD) can be classified into those with postural instability and gait difficulty (PIGD subtype) and those manifesting tremor as the main symptoms (non-PIGD subtype). In a prospective cohort study of 113 people with PD we aimed to contrast fall rates and circumstances a...

Descripción completa

Detalles Bibliográficos
Autores principales: Pelicioni, Paulo H. S., Menant, Jasmine C., Latt, Mark D., Lord, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616496/
https://www.ncbi.nlm.nih.gov/pubmed/31234571
http://dx.doi.org/10.3390/ijerph16122216
_version_ 1783433521910513664
author Pelicioni, Paulo H. S.
Menant, Jasmine C.
Latt, Mark D.
Lord, Stephen R.
author_facet Pelicioni, Paulo H. S.
Menant, Jasmine C.
Latt, Mark D.
Lord, Stephen R.
author_sort Pelicioni, Paulo H. S.
collection PubMed
description People with Parkinson’s disease (PD) can be classified into those with postural instability and gait difficulty (PIGD subtype) and those manifesting tremor as the main symptoms (non-PIGD subtype). In a prospective cohort study of 113 people with PD we aimed to contrast fall rates and circumstances as well as a range of disease-related, clinical, and functional measures between the PD subtypes. Compared with non-PIGD participants, PIGD participants were significantly more likely to suffer more falls overall as well as more falls due to freezing of gait, balance-related falls and falls at home. The PIGD group also performed significantly worse in a range of fall-related clinical and functional measures including general cognitive status, executive function, quadriceps muscle strength, postural sway and the timed up and go test. These findings document the extent to which people with the PIGD subtype are at increased risk of falls, the circumstances in which they fall and their disease-related, clinical and functional impairments.
format Online
Article
Text
id pubmed-6616496
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-66164962019-07-18 Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances Pelicioni, Paulo H. S. Menant, Jasmine C. Latt, Mark D. Lord, Stephen R. Int J Environ Res Public Health Article People with Parkinson’s disease (PD) can be classified into those with postural instability and gait difficulty (PIGD subtype) and those manifesting tremor as the main symptoms (non-PIGD subtype). In a prospective cohort study of 113 people with PD we aimed to contrast fall rates and circumstances as well as a range of disease-related, clinical, and functional measures between the PD subtypes. Compared with non-PIGD participants, PIGD participants were significantly more likely to suffer more falls overall as well as more falls due to freezing of gait, balance-related falls and falls at home. The PIGD group also performed significantly worse in a range of fall-related clinical and functional measures including general cognitive status, executive function, quadriceps muscle strength, postural sway and the timed up and go test. These findings document the extent to which people with the PIGD subtype are at increased risk of falls, the circumstances in which they fall and their disease-related, clinical and functional impairments. MDPI 2019-06-23 2019-06 /pmc/articles/PMC6616496/ /pubmed/31234571 http://dx.doi.org/10.3390/ijerph16122216 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pelicioni, Paulo H. S.
Menant, Jasmine C.
Latt, Mark D.
Lord, Stephen R.
Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances
title Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances
title_full Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances
title_fullStr Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances
title_full_unstemmed Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances
title_short Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances
title_sort falls in parkinson’s disease subtypes: risk factors, locations and circumstances
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616496/
https://www.ncbi.nlm.nih.gov/pubmed/31234571
http://dx.doi.org/10.3390/ijerph16122216
work_keys_str_mv AT pelicionipaulohs fallsinparkinsonsdiseasesubtypesriskfactorslocationsandcircumstances
AT menantjasminec fallsinparkinsonsdiseasesubtypesriskfactorslocationsandcircumstances
AT lattmarkd fallsinparkinsonsdiseasesubtypesriskfactorslocationsandcircumstances
AT lordstephenr fallsinparkinsonsdiseasesubtypesriskfactorslocationsandcircumstances