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Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances
People with Parkinson’s disease (PD) can be classified into those with postural instability and gait difficulty (PIGD subtype) and those manifesting tremor as the main symptoms (non-PIGD subtype). In a prospective cohort study of 113 people with PD we aimed to contrast fall rates and circumstances a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616496/ https://www.ncbi.nlm.nih.gov/pubmed/31234571 http://dx.doi.org/10.3390/ijerph16122216 |
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author | Pelicioni, Paulo H. S. Menant, Jasmine C. Latt, Mark D. Lord, Stephen R. |
author_facet | Pelicioni, Paulo H. S. Menant, Jasmine C. Latt, Mark D. Lord, Stephen R. |
author_sort | Pelicioni, Paulo H. S. |
collection | PubMed |
description | People with Parkinson’s disease (PD) can be classified into those with postural instability and gait difficulty (PIGD subtype) and those manifesting tremor as the main symptoms (non-PIGD subtype). In a prospective cohort study of 113 people with PD we aimed to contrast fall rates and circumstances as well as a range of disease-related, clinical, and functional measures between the PD subtypes. Compared with non-PIGD participants, PIGD participants were significantly more likely to suffer more falls overall as well as more falls due to freezing of gait, balance-related falls and falls at home. The PIGD group also performed significantly worse in a range of fall-related clinical and functional measures including general cognitive status, executive function, quadriceps muscle strength, postural sway and the timed up and go test. These findings document the extent to which people with the PIGD subtype are at increased risk of falls, the circumstances in which they fall and their disease-related, clinical and functional impairments. |
format | Online Article Text |
id | pubmed-6616496 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-66164962019-07-18 Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances Pelicioni, Paulo H. S. Menant, Jasmine C. Latt, Mark D. Lord, Stephen R. Int J Environ Res Public Health Article People with Parkinson’s disease (PD) can be classified into those with postural instability and gait difficulty (PIGD subtype) and those manifesting tremor as the main symptoms (non-PIGD subtype). In a prospective cohort study of 113 people with PD we aimed to contrast fall rates and circumstances as well as a range of disease-related, clinical, and functional measures between the PD subtypes. Compared with non-PIGD participants, PIGD participants were significantly more likely to suffer more falls overall as well as more falls due to freezing of gait, balance-related falls and falls at home. The PIGD group also performed significantly worse in a range of fall-related clinical and functional measures including general cognitive status, executive function, quadriceps muscle strength, postural sway and the timed up and go test. These findings document the extent to which people with the PIGD subtype are at increased risk of falls, the circumstances in which they fall and their disease-related, clinical and functional impairments. MDPI 2019-06-23 2019-06 /pmc/articles/PMC6616496/ /pubmed/31234571 http://dx.doi.org/10.3390/ijerph16122216 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pelicioni, Paulo H. S. Menant, Jasmine C. Latt, Mark D. Lord, Stephen R. Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances |
title | Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances |
title_full | Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances |
title_fullStr | Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances |
title_full_unstemmed | Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances |
title_short | Falls in Parkinson’s Disease Subtypes: Risk Factors, Locations and Circumstances |
title_sort | falls in parkinson’s disease subtypes: risk factors, locations and circumstances |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616496/ https://www.ncbi.nlm.nih.gov/pubmed/31234571 http://dx.doi.org/10.3390/ijerph16122216 |
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