Cargando…

Analgesic and Antidepressant Effects of Oltipraz on Neuropathic Pain in Mice by Modulating Microglial Activation

Nerve injury provokes microglial activation, contributing to the sensory and emotional disorders associated with neuropathic pain that do not completely resolve with treatment. In C57BL/6J mice with neuropathic pain induced by chronic constriction of the sciatic nerve (CCI), we evaluated the effects...

Descripción completa

Detalles Bibliográficos
Autores principales:	Díaz, Andrés Felipe, Polo, Sara, Gallardo, Núria, Leánez, Sergi, Pol, Olga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616658/ https://www.ncbi.nlm.nih.gov/pubmed/31234342 http://dx.doi.org/10.3390/jcm8060890

Ejemplares similares

Treatment With the Delta Opioid Agonist UFP-512 Alleviates Chronic Inflammatory and Neuropathic Pain: Mechanisms Implicated
por: Polo, Sara, et al.
Publicado: (2019)

Carbon Monoxide Reduces Neuropathic Pain and Spinal Microglial Activation by Inhibiting Nitric Oxide Synthesis in Mice
por: Hervera, Arnau, et al.
Publicado: (2012)

Analgesic Mechanisms of Antidepressants for Neuropathic Pain
por: Obata, Hideaki
Publicado: (2017)

Lack of mechanical and thermal allodynia, and thermal hyperalgesia induced by peripheral neuropathic pain in NOS2 knockout mice
por: Hervera, Arnau, et al.
Publicado: (2009)

The Spinal Cord Expression of Neuronal and Inducible Nitric Oxide Synthases and Their Contribution in the Maintenance of Neuropathic Pain in Mice
por: Hervera, Arnau, et al.
Publicado: (2010)

Sulforaphane Inhibited the Nociceptive Responses, Anxiety- and Depressive-Like Behaviors Associated With Neuropathic Pain and Improved the Anti-allodynic Effects of Morphine in Mice
por: Ferreira-Chamorro, Pablo, et al.
Publicado: (2018)

Peripheral effects of morphine and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling
por: Hervera, Arnau, et al.
Publicado: (2011)

Analysis of the analgesic effects of tricyclic antidepressants on neuropathic pain, diabetic neuropathic pain, and fibromyalgia in rat models
por: Qin, Zhenlong, et al.
Publicado: (2020)

Elucidating the Anti-Tumorigenic Efficacy of Oltipraz, a Dithiolethione, in Glioblastoma
por: Kapoor-Narula, Upasana, et al.
Publicado: (2022)

The Effects of Cobalt Protoporphyrin IX and Tricarbonyldichlororuthenium (II) Dimer Treatments and Its Interaction with Nitric Oxide in the Locus Coeruleus of Mice with Peripheral Inflammation
por: Moreno, Patricia, et al.
Publicado: (2019)

Modulation of microglial activation by antidepressants
por: Mariani, Nicole, et al.
Publicado: (2022)

The Anxiolytic and Antidepressant Effects of Diallyl Disulfide and GYY4137 in Animals with Chronic Neuropathic Pain
por: Bai, Xue, et al.
Publicado: (2021)

The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice
por: Castany, Sílvia, et al.
Publicado: (2016)

Neuronal and microglial mechanisms of neuropathic pain
por: Zhuo, Min, et al.
Publicado: (2011)

Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain
por: Popiolek-Barczyk, Katarzyna, et al.
Publicado: (2016)

The analgesic and antidepressant properties of dihydroartemisinine in the neuropathic pain mice: By the downregulation of HnRNPA1 in the spinal cord and hippocampus
por: Zhu, Chunyan, et al.
Publicado: (2022)

Effects of norepinephrine on microglial neuroinflammation and neuropathic pain
por: Zou, He‐Lin, et al.
Publicado: (2021)

Hydrogen Sulfide Increases the Analgesic Effects of µ- and δ-Opioid Receptors during Neuropathic Pain: Pathways Implicated
por: Bai, Xue, et al.
Publicado: (2022)

Modulation of microglial function by the antidepressant drug venlafaxine
por: Dubovický, Michal, et al.
Publicado: (2014)

Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain
por: Toth, Cory C, et al.
Publicado: (2010)

The Inhibitory Effects of Cobalt Protoporphyrin IX and Cannabinoid 2 Receptor Agonists in Type 2 Diabetic Mice
por: McDonnell, Christina, et al.
Publicado: (2017)

The induction of the transcription factor Nrf2 enhances the antinociceptive effects of delta-opioid receptors in diabetic mice
por: McDonnell, Christina, et al.
Publicado: (2017)

p38 MAPK, microglial signaling, and neuropathic pain
por: Ji, Ru-Rong, et al.
Publicado: (2007)

Regulation of neuropathic pain by microglial Orai1 channels
por: Tsujikawa, Shogo, et al.
Publicado: (2023)

The temporal and spatial signature of microglial transcriptome in neuropathic pain
por: Liu, Zeyuan, et al.
Publicado: (2023)

The Antinociceptive Effects of JWH-015 in Chronic Inflammatory Pain Are Produced by Nitric Oxide-cGMP-PKG-KATP Pathway Activation Mediated by Opioids
por: Negrete, Roger, et al.
Publicado: (2011)

Common mechanisms of pain and depression: are antidepressants also analgesics?
por: Nekovarova, Tereza, et al.
Publicado: (2014)

Oltipraz ameliorates the progression of steatohepatitis in Nrf2-null mice fed a high-fat diet
por: Kamisako, Toshinori, et al.
Publicado: (2022)

Modification of neuropathic pain sensation through microglial ATP receptors
por: Inoue, Kazuhide, et al.
Publicado: (2007)

Analgesic effects of medicinal plants and phytochemicals on chemotherapy‐induced neuropathic pain through glial modulation
por: Lee, Ji Hwan, et al.
Publicado: (2021)

Different analgesic effects of adenosine between postoperative and neuropathic pain
por: Yamaoka, Gotaro, et al.
Publicado: (2012)

Analgesic Effects of Dexmedetomidine in Vincristine-Evoked Painful Neuropathic Rats
por: Park, Hue Jung, et al.
Publicado: (2012)

Analgesic Effect of Harpagophytum procumbens on Postoperative and Neuropathic Pain in Rats
por: Lim, Dong Wook, et al.
Publicado: (2014)

Nefopam: Another Pragmatic Analgesic in Managing Chronic Neuropathic Pain
por: Nair, Abhijit S
Publicado: (2019)

Analgesic Activity of Cinnabarinic Acid in Models of Inflammatory and Neuropathic Pain
por: Notartomaso, Serena, et al.
Publicado: (2022)

Analgesic effect of α-terpineol on neuropathic pain induced by chronic constriction injury in rat sciatic nerve: Involvement of spinal microglial cells and inflammatory cytokines
por: Soleimani, Mohsen, et al.
Publicado: (2019)

Antitumoral Effects of Tricyclic Antidepressants: Beyond Neuropathic Pain Treatment
por: Asensi-Cantó, Antonio, et al.
Publicado: (2022)

Synaptotagmin 1 Is Involved in Neuropathic Pain and Electroacupuncture-Mediated Analgesic Effect
por: Wan, Juan, et al.
Publicado: (2020)

Analgesic Effect of Bumetanide on Neuropathic Pain in Patients With Spinal Cord Injury
por: Nasirinezhad, Farinaz, et al.
Publicado: (2021)

Tuina for peripherally-induced neuropathic pain: A review of analgesic mechanism
por: Liu, Zhi-Feng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_chu87jh2m4e9ka8gi6ib1n2vsd